COUNTERCURRENT CHROMATOGRAPH

Countercurrent chromatography, one of the oldest techniques for achieving separation, is based on partitioning of solutes between a stream of liquid mobile phase and a liquid stationary phase.  EYLA countercurrent chromatographs offers several inherent advantages; large sample capacity, small solvent consumption, inert environment and low operating pressure.   In addition, simplicity of operation and the ability to separate anything from milligram to gram quantities has led to the widespread acceptance, especially in the field of natural products research.

Model DCC-3000 
Droplet Countercurrent Chromatograph
The mobile phase in the form of droplets is pumped into series of columns containing the immiscible stationary liquid phase.  When the sample components are introduced into the mobile phase, separation is achieved     due to the difference in the partition coefficient between the two phases. Several kinds of liquid are can be used for the two immiscible phases, such as water, methanol and chloroform.  The DCC-3000 includes 300 columns of 400mm length enclosed in a thermostated oven.  The column hardware  can either be glass or Teflon.

 

 

Model RLCC-1000 
Rotation Locular Countercurrent Chromatograph
Separation of solutes is achieved by partitioning between a steady stream of mobile phase and the stationary phase filled in the locular column system.  The RLCC-3000 consists of 16 glass columns, of 500mm length, each containing  37 chambers or locules formed by Teflon disks and spacers.  The RLCC-1000 can be used with wide range of solvent system, including emulsive solvent